About Us

Our Mission

Our mission is lead the way in finding a cure for TANGO2 related disease. We will do this by helping to fund, coordinate and guide scientific research that leads to a better understanding of how TANGO2 mutations affect people at the most basic cellular and biochemical pathway levels.

Meet Our Leadership Team   |    Meet Our Scientific Advisory Board

Our History

TANGO2 as a gene related to human disease was first discovered in 2016. Rapid advances in technology and techniques such as Whole Exome Sequencing (WES) have allowed researchers to identify and catalog rare genetic disorders at a faster pace than ever before. For those of us with older children, a diagnosis began to explain the struggles and challenges our children (and we as families) have faced after many years of searching for an answer.

What became very clear as we as parents communicated with one another and learned more of each others unique experiences with our children and the medical community at large, is that not nearly enough was known about how it is that TANGO2 mutations affected our children at the most basic cellular, metabolic and biochemical level. The talented and caring professionals that were working so hard to help our children, lacked the benefit of this basic research and were doing the best they could with very limited research and data.

This is where the idea for the TANGO2 Research Foundation was borne in late 2017. It is our hope that by helping to fund, coordinate and guide the efforts of researchers, scientists and doctors, we can rapidly accelerate the understanding around TANGO2 and pave the way to future therapies and positive outcomes for our loved ones.

Registered Not-for-Profit 501(c)(3) Corporation

The TANGO2 Research Foundation is registered as a not-for-profit corporation under the laws of the State of CT, and is exempt from United States federal income taxes under section 501(c)(3) of the Internal Revenue Code. Click here to view our 501 (c) (3) Determination Letter.